LODERMA [Dexpanthenol] 50 mg Cream for external use

instructions for the medical use of the medicinal product

LODERMA

Tradename: Loderma, Лодерма

International non-proprietary name or generic name: dexpanthenol, декспантенол

Dosage form: cream for external use.

Composition per 1 g of cream:

active substance: dexpanthenol 50 mg.

excipients: cetyl stearyl alcohol, glyceryl mono- and distearate, white petrolatum, light liquid paraffin, stearic acid, ethylparaben, glycerin, peregal O, purified water.

Pharmacotherapeutic group:  Tissue regeneration stimulator

ATX code: D03AX03

Pharmacological properties

Pharmacodynamics

Dexpanthenol is a derivative of pantothenic acid. Pantothenic acid - a water-soluble B vitamin (vitamin B5) - is an integral part of coenzyme A. Stimulates skin regeneration, normalizes cellular metabolism, increases the strength of collagen fibers. An increased need for pantothenic acid is observed when the skin or tissues are damaged, and its deficiency can be compensated for by the local use of dexpanthenol.

Pharmacokinetics

Dexpanthenol is quickly absorbed by the skin (rapidly absorbed) and converted into pantothenic acid. Binds to plasma proteins (mainly albumin and β-globulin). Pantothenic acid is not metabolized in the body and is excreted unchanged.

Indications for use

Violation of the integrity of the skin: healing of burns (including sunburn), minor skin damage (including abrasions, cuts, cracks); prevention and treatment of dry skin, incl. and as a consequence of dermatitis of various origins; daily care of areas of the skin most exposed to external factors (face, hands); care of the mammary glands during lactation (cracks and redness of the nipples of the mammary gland); caring for infants and infants (diaper rash, diaper dermatitis).

Contraindications

Hypersensitivity to dexpanthenol and the components of the drug.

Method of administration and dosage

Externally.

The cream is applied in a thin layer 1-2 times a day to the affected surface and rubbed in lightly.

When caring for the mammary gland, the cream is applied to the surface of the nipples after each feeding and should be washed off before feeding the baby.

When caring for infants, the cream is applied with each diaper change.

Use during pregnancy and breastfeeding

Indications: cracks and inflammation of the nipples of the breast in nursing mothers.

Side effect

Side effects develop extremely rarely. Mild allergic reactions are possible (for example, redness, rash, urticaria, skin irritation, itching).

If any of the side effects indicated in the instructions worsen, or any other side effects not listed in the instructions are noted, you should immediately inform your doctor.

Interaction with other medicinal products

There is no data on drug interactions.

Special instructions and precautions

During pregnancy and breastfeeding, use on large areas should be avoided.

Treatment of trophic ulcers and poorly healing skin grafts should be carried out under the supervision of the attending physician.

Do not apply to wet wounds.

Avoid contact with eyes or mucous membranes.

Overdose

No cases of overdose have been reported.

Release form

30 g of cream in an aluminum tube with a polypropylene lid. One tube along with instructions for use in a cardboard box.

Storage conditions

Store at temperatures below 30°C.

Keep out of the reach of children!

Shelf life

3 years. Do not use after the expiration date stated on the package.

Vacation conditions

By prescription.